BRAIN Blog

Improved method for optimizing resolution of magnetic particle imaging with important medical applications… New technique allows for successful 3D imaging of deep brain tissue in awake animals… Development of a stable deep brain stimulation electrode for long-term implantation…

The “State of the Brain” Keystone Symposium offered a platform for investigators and funding groups to share their current scientific discoveries and discuss new and exciting future brain-related research….

Candidate viral entry receptor for Zika Virus in neural stem cells identified… researchers create 3D topographical map of motor cortex output projections… discovery of new type of On bipolar cell and spatiotemporal wiring specificity in retinal computation of direction…

Controlling neurons with radio waves…inhibition drives whisking behavior in mice…a new type of bright, fast, red fluorescent protein voltage indicator.

Radio waves regulate feeding behavior in mice by turning hypothalamus neurons on or off

The articles cover a wide range of topics related to BRAIN Initiative goals, from multi-scale neural recordings to deep brain stimulation to technologies for recording activity in human brains such as EEG and ECoG.

Widespread delivery of genes across the blood brain barrier…light-activated glutamate receptors become more specialized, used in vivo for first time…manipulations of intraocular pressure are used to measure intracranial pressure…researchers discover new types of retinal ganglion…

Microbubbles help lasers focus on neurons deep in the brain…New genetically encoded voltage indicator reveals individual action potentials…Scientists use RNA sequencing to classify neurons in primary visual cortex.

Researchers have genetically modified the entire family of GABA_A receptor subtypes, which mediate inhibitory synaptic transmission in the brain, to make them controllable with pulses of light with high spatial, temporal, and biochemical precision.

Genetic analysis of different populations of neural stem cells indicates that one group of cells—the outer radial glia—gives rise to the majority of neurons in the upper layers of the neocortex that are associated with higher-level information processing and thinking, suggesting that these…

Researchers have created an expandable, open-source anatomical atlas of the entire zebrafish brain, called the Z-Brain, and mapped onto it whole-brain activity occurring during multiple behaviors